Neutron beam optimization based on a 7Li(p,n)7Be reaction for treatment of deep-seated brain tumors by BNCT

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Zahra Ahmadi Ganjeh and S. Farhad Masoudi. Neutron beam optimization based on a 7Li(p,n)7Be reaction for treatment of deep-seated brain tumors by BNCT[J]. Chinese Physics C, 2014, 38(10): 108203. doi: 10.1088/1674-1137/38/10/108203
Zahra Ahmadi Ganjeh and S. Farhad Masoudi. Neutron beam optimization based on a 7Li(p,n)7Be reaction for treatment of deep-seated brain tumors by BNCT[J]. Chinese Physics C, 2014, 38(10): 108203.  doi: 10.1088/1674-1137/38/10/108203 shu
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Received: 2013-11-04
Revised: 1900-01-01
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Neutron beam optimization based on a 7Li(p,n)7Be reaction for treatment of deep-seated brain tumors by BNCT

    Corresponding author: S. Farhad Masoudi,

Abstract: Neutron beam optimization for accelerator-based Boron Neutron Capture Therapy (BNCT) is investigated using a 7Li(p,n)7Be reaction. Design and optimization have been carried out for the target, cooling system, moderator, filter, reflector, and collimator to achieve a high flux of epithermal neutron and satisfy the IAEA criteria. Also, the performance of the designed beam in tissue is assessed by using a simulated Snyder head phantom. The results show that the optimization of the collimator and reflector is critical to finding the best neutron beam based on the 7Li(p,n)7Be reaction. Our designed beam has 2.49×109n/cm2s epithermal neutron flux and is suitable for BNCT of deep-seated brain tumors.

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