Designing of the 14 MeV neutron moderator for BNCT

CHENG Dao-Wen; LU Jing-Bin; YANG Dong; LIU Yu-Min; WANG Hui-Dong; MA Ke-Yan

doi:10.1088/1674-1137/36/9/020

Chinese Physics C> 2012, Vol. 36> Issue(9) : 905-908 DOI: 10.1088/1674-1137/36/9/020

Designing of the 14 MeV neutron moderator for BNCT

Abstract
HTML
Reference
Related

PDF

Abstract：
In boron neutron capture therapy (BNCT), the ratio of the fast neutron flux to the neutron flux in the tumor (RFNT) must be less than 3%. If a D-T neutron generator is used in BNCT, the 14 MeV neutron moderator must be optimized to reduce the RFNT. Based on the neutron moderation theory and the simulation results, tungsten, lead and diamond were used to moderate the 14 MeV neutrons. Satisfying RFNT of less than 3%, the maximum neutron flux in the tumor was achieved with a three-layer moderator comprised of a 3 cm thick tungsten layer, a 14 cm thick lead layer and a 21 cm thick diamond layer.

References

[1]

Elshahat B A, Naqvi A A, Khalid Abdalla et al. J. Radioanal. Nucl. Chem., 2007, 274(3): 539-543[2] Veróica A, Trivillin, Elisa M Heber, Monica Rao et al. Radiat. Environ. Bioph., 2008, 47(efeq1): 147-151[3] CHENG Dao-wen, GU De-shan, LIU Lin-mao et al. Chinese Physics C, 2010, 34(5): 606-609[4] GU D S, JING S W, SANG H F et al. J. Radioanal. Nucl. Chem., 2004, 262(2): 493-496[5] Borisov I. Phys. PaRFNT. Nuclei., 2011, 42(5): 713-781[6] Frederick Hawthorne M, Mark W Lee et al. J. Neuro- Oncol., 2003, 62(efeq1): 33-45[7] Moss R L, Aizawa O, Beynon D et al. J. Neuro- Oncol., 1997, 33(1-2): 27-40[8] Natouh S A. AL-Nawah., 2008, 8(12): 34-42[9] Agosteo S, Curzio G. Nucl. Instrum. Methods Phys. Res., Sect. A, 2002, 476: 106-112

[1]	Dong Bai , Zhongzhou Ren , Tiekuang Dong . Two-neutron halo state of ¹⁵B around 3.48 MeV by a three-body model. Chinese Physics C, 2018, 42(6): 064103. doi: 10.1088/1674-1137/42/6/064103
[2]	Chang-Lin Lan , Yi Zhang , Tao Lv , Bao-Lin Xie , Meng Peng , Ze-En Yao , Jin-Gen Chen , Xiang-Zhong Kong . Determination of neutron capture cross sections of ²³²Th at 14.1 MeV and 14.8 MeV using the neutron activation method. Chinese Physics C, 2017, 41(4): 044002. doi: 10.1088/1674-1137/41/4/044002
[3]	Yong-Tao Liu , Gui-Rong Huang , Lei Shang , Hong-Xiang Lin , Bai-Ting Du . A method for designing a variable-channel high-power cavity combiner. Chinese Physics C, 2016, 40(8): 087002. doi: 10.1088/1674-1137/40/8/087002
[4]	LI Yan-Yan , ZHANG Xue-Ying , JU Yong-Qin , MA Fei , ZHANG Hong-Bin , CHEN Liang , GE Hong-Lin , WAN Bo , LUO Peng , ZHOU Bin , ZHANG Yan-Bin , LI Jian-Yang , XU Jun-Kui , WANG Song-Lin , YANG Yong-Wei , YANG Lei . Study of neutron spectra in a water bath from a Pb target irradiated by 250 MeV protons. Chinese Physics C, 2015, 39(4): 044001. doi: 10.1088/1674-1137/39/4/044001
[5]	SUN Xiao-Jun , YU Cheng-Gang , WANG Ning , YANG Yong-Xu , PAN Cheng-Hua . Pre-neutron-emission mass distributions for reaction²³⁸U(n, f) up to 60 MeV. Chinese Physics C, 2015, 39(1): 014102. doi: 10.1088/1674-1137/39/1/014102
[6]	Zahra Ahmadi Ganjeh , S. Farhad Masoudi . Neutron beam optimization based on a ⁷Li(p,n)⁷Be reaction for treatment of deep-seated brain tumors by BNCT. Chinese Physics C, 2014, 38(10): 108203. doi: 10.1088/1674-1137/38/10/108203
[7]	YANG Xiao-Peng , YU Bo-Xiang , LI Yi-Guo , PENG Dan , LU Jin , ZHANG Gao-Long , ZHAO Hang , ZHANG Ai-Wu , LI Chun-Yang , LIU Wan-Jin , HU Tao , . Neutron collimator design of neutron radiography basedon the BNCT facility. Chinese Physics C, 2014, 38(2): 028201. doi: 10.1088/1674-1137/38/2/028201
[8]	PEI Shi-Lun , CHI Yun-Long , WANG Shu-Hong , PEI Guo-Xi , ZHOU Zu-Sheng , HOU Mi , Mykola Ayzatskiy , Ivan Karnaukhov , Volodymyr Kushnir , Viktor Mytrochenko , Andrey Zelinsky . Beam dynamics studies on the 100 MeV/100 kWelectron linear accelerator for NSCKIPT neutron source. Chinese Physics C, 2012, 36(7): 653-660. doi: 10.1088/1674-1137/36/7/015
[9]	PU Zhong-Sheng , FAN Kang-Kang , SONG Guan-Qiang . Cross section measurements for (n, p) reaction on stannum isotopes at neutron energies from 13.5 to 14.6 MeV. Chinese Physics C, 2011, 35(5): 445-448. doi: 10.1088/1674-1137/35/5/007
[10]	FANG Kai-Hong , XU Xiao-San , LAN Chang-Lin , YUAN Ji-Long , KONG Xiang-Zhong . Cross-section measurement for Ni(n,x)^58(m+g)Co,Ni(n, x)^60mCo, Ni(n,x)⁶¹Co and Ni(n,x)^62mCo reactions induced by neutrons around 14MeV. Chinese Physics C, 2008, 32(4): 251-253. doi: 10.1088/1674-1137/32/4/002
[11]	LI Gang , DENG Li . Optimized Voxel Model Construction and Simulation Research in BNCT. Chinese Physics C, 2006, 30(2): 171-177.
[12]	HE Guo-Zhu , TUO Fei , KONG Xiang-Zhong . (n,2n),(n,p) and (n,α) Reactions Cross-Sections Measurement on Selenium Isotopes at Neutron Energy of 14MeV. Chinese Physics C, 2006, 30(9): 844-847.
[13]	ZHANG Feng , KONG Xiang-Zhong . Measurement of Cross Sections for Pb(n,x)²⁰³Hg,W(n,x)¹⁸²Ta and W(n,x)¹⁸³Ta Reactions Induced by 14 MeV Neutrons. Chinese Physics C, 2003, 27(1): 28-30.
[14]	LIU Zu-Hua . Neutron Halo of the Excited States in ¹⁴C. Chinese Physics C, 2003, 27(2): 135-137.
[15]	LI Guo-Zheng , JIANG Jing-He . CROSS SECTION MEASUREMENTS OF NUCLEAR REACTIONS FOR Ni INDUCED BY ¹⁴MeV NEUTRONS. Chinese Physics C, 1990, 14(11): 1023-1030.
[16]	GUO Zhong-Yan , SHEN Wen-Qing , ZHU Yong-Tai , QIAO Wei-Min , YIN Shu-Zhi , ZHAN Wen-Long , WU En-Jiu . THE RESEARCH OF DIC PROCESS INDUCED BY 92MeV AND 77MeV ¹⁴N AND ²⁷Al. Chinese Physics C, 1987, 11(4): 496-504.
[17]	YIN Shu-Zhi , ZHU Yong-Tai , SHEN Wen-Qing , GUO Zhong-Yan , ZHAN Wen-Long , QIAO Wei-Min , WU En-Jiu , ZHENG Zhi-Hao . A RESEARCH FOR THE DEEP INELASTIC COLLISION INDUCED BY 93MeV ¹⁴N ON ^natCa. Chinese Physics C, 1987, 11(2): 259-267.
[18]	YAO Li-Shan , ZHOU En-Chen , CAI Dun-Jiu . A SYSTEMATIC STUDY OF (n, 2n) CROSS SECTION AT 14MeV. Chinese Physics C, 1987, 11(4): 533-542.
[19]	SHEN Wen-Qing , ZHU Yong-Tai , ZHANG Yu-Hu , ZHAN Wen-Long , QIAO Wei-Min , ZHANG Zhen , WU En-Jiu , YEN Shu-Zhi , FAN Guo-Ying , MIAO He-Bin , ZHENG Zhi-Hao . RESEARCH OF THE ELESTIC SCATTERING INDUCED BY 7—5 MeV/A ¹⁴N ON ⁵⁹Co AND ⁵¹V. Chinese Physics C, 1985, 9(6): 718-722.
[20]	WANG BAO-AN , FENG JIA-ZHEN , LIU ZHAO-YUAN , YANG HUA-ZHONG , YAO LI-SHAN . THE MECHANISM OF THE REACTION ¹⁴¹pr(n,α)¹³⁸La AT En=14 MeV. Chinese Physics C, 1981, 5(5): 636-640.

Access

Get Citation

CHENG Dao-Wen, LU Jing-Bin, YANG Dong, LIU Yu-Min, WANG Hui-Dong and MA Ke-Yan. Designing of the 14 MeV neutron moderator for BNCT[J]. Chinese Physics C, 2012, 36(9): 905-908. doi: 10.1088/1674-1137/36/9/020

RIS(for EndNote,Reference Manager,ProCite)

BibTex

Txt

Milestone

Received: 2011-12-23
Revised: 1900-01-01

Article Metric

Article Views(2217)
PDF Downloads(400)
Cited by(0)

Policy on re-use

To reuse of subscription content published by CPC, the users need to request permission from CPC, unless the content was published under an Open Access license which automatically permits that type of reuse.

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Designing of the 14 MeV neutron moderator for BNCT

Corresponding author: CHENG Dao-Wen,

Received Date: 2011-12-23

Accepted Date: 1900-01-01

Available Online: 2012-09-05

Abstract: In boron neutron capture therapy (BNCT), the ratio of the fast neutron flux to the neutron flux in the tumor (RFNT) must be less than 3%. If a D-T neutron generator is used in BNCT, the 14 MeV neutron moderator must be optimized to reduce the RFNT. Based on the neutron moderation theory and the simulation results, tungsten, lead and diamond were used to moderate the 14 MeV neutrons. Satisfying RFNT of less than 3%, the maximum neutron flux in the tumor was achieved with a three-layer moderator comprised of a 3 cm thick tungsten layer, a 14 cm thick lead layer and a 21 cm thick diamond layer.

HTML

Reference (1)

Designing of the 14 MeV neutron moderator for BNCT

Abstract：

References

Access

Article Metrics

Metrics

通讯作者: 陈斌, bchen63@163.com

Email This Article