Translocation of Inhaled TiO2 Nanoparticles Along Olfactory Nervous System to Brain Studied by Synchrotron Radiation X-Ray Fluorescence

Get Citation
WANG Jiang-Xue, CHEN Chun-Ying, SUN Jin, YU Hong-Wei, LI Yu-Feng, LI Bai, XING Li, HUANG Yu-Ying, HE Wei, GAO Yu-Xi, CHAI Zhi-Fang and ZHAO Yu-Liang. Translocation of Inhaled TiO2 Nanoparticles Along Olfactory Nervous System to Brain Studied by Synchrotron Radiation X-Ray Fluorescence[J]. Chinese Physics C, 2005, 29(S1): 76-79.
WANG Jiang-Xue, CHEN Chun-Ying, SUN Jin, YU Hong-Wei, LI Yu-Feng, LI Bai, XING Li, HUANG Yu-Ying, HE Wei, GAO Yu-Xi, CHAI Zhi-Fang and ZHAO Yu-Liang. Translocation of Inhaled TiO2 Nanoparticles Along Olfactory Nervous System to Brain Studied by Synchrotron Radiation X-Ray Fluorescence[J]. Chinese Physics C, 2005, 29(S1): 76-79. shu
Milestone
Received: 2005-10-28
Revised: 1900-01-01
Article Metric

Article Views(4325)
PDF Downloads(700)
Cited by(0)
Policy on re-use
To reuse of subscription content published by CPC, the users need to request permission from CPC, unless the content was published under an Open Access license which automatically permits that type of reuse.
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Email This Article

Title:
Email:

Translocation of Inhaled TiO2 Nanoparticles Along Olfactory Nervous System to Brain Studied by Synchrotron Radiation X-Ray Fluorescence

    Corresponding author: CHEN Chun-Ying,
  • Institute of High Energy Physics, CAS,Beijing 100049,China2 Graduate School of the CAS,Beijing 100049,China

Abstract: Nanosized TiO2 is widely used for cleaning air,antibacterial and decomposing organic in wastewater for its highly photocatalytic function. TiO2 inhalation via respiratory tracts is the most common route of its exposure in industry and environment. After inhalation by human or rodents, TiO2 can induce inflammation and pulmonary lesions, which was reported to even cause lung cancer by long-term exposure. In this paper, Synchrotron Radiation X-ray Fluorescence was employed to investigate the distribution of TiO2 in the olfactory bulb and brain of mice after inhalation of TiO2 particles suspension.The results showed that TiO2 could enter the olfactory nerve layer (ON), granular cell layer of olfactory bulb (Gro), and olfactory ventricle (OV) and further the hippocampus, thalamus,and CA3 area of the brain through the olfactory nervous system.The distribution area of microsized TiO2 was wider than that of nanosized TiO2.

    HTML

Reference (1)

目录

/

DownLoad:  Full-Size Img  PowerPoint
Return
Return