Fast and accurate generation method of PSF-based system matrix for PET reconstruction

null

doi:10.1088/1674-1137/41/4/048201

近期发现有不法分子冒充我刊与作者联系，借此进行欺诈等不法行为，请广大作者加以鉴别，如遇诈骗行为，请第一时间与我刊编辑部联系确认（《中国物理C》（英文）编辑部电话：010-88235947,010-88236950），并作报警处理。

本刊再次郑重声明：

（1）本刊官方网址为cpc.ihep.ac.cn和https://iopscience.iop.org/journal/1674-1137

（2）本刊采编系统作者中心是投稿的唯一路径，该系统为ScholarOne远程稿件采编系统，仅在本刊投稿网网址（https://mc03.manuscriptcentral.com/cpc）设有登录入口。本刊不接受其他方式的投稿，如打印稿投稿、E-mail信箱投稿等，若以此种方式接收投稿均为假冒。

（3）所有投稿均需经过严格的同行评议、编辑加工后方可发表，本刊不存在所谓的“编辑部内部征稿”。如果有人以“编辑部内部人员”名义帮助作者发稿，并收取发表费用，均为假冒。

《中国物理C》（英文）编辑部

2024年10月30日

Chinese Physics C> 2017, Vol. 41> Issue(4) : 048201 DOI: 10.1088/1674-1137/41/4/048201

Fast and accurate generation method of PSF-based system matrix for PET reconstruction

null

Abstract
HTML
Reference
Related

PDF

Abstract：
This work investigates the positional single photon incidence response (P-SPIR) to provide an accurate point spread function (PSF)-contained system matrix and its incorporation within the image reconstruction framework. Based on the Geant4 Application for Emission Tomography (GATE) simulation, P-SPIR theory takes both incidence angle and incidence position of the gamma photon into account during crystal subdivision, instead of only taking the former into account, as in single photon incidence response (SPIR). The response distribution obtained in this fashion was validated using Monte Carlo simulations. In addition, two-block penetration and normalization of the response probability are introduced to improve the accuracy of the PSF. With the incorporation of the PSF, the homogenization model is then analyzed to calculate the spread distribution of each line-of-response (LOR). A primate PET scanner, Eplus-260, developed by the Institute of High Energy Physics, Chinese Academy of Sciences (IHEP), was employed to evaluate the proposed method. The reconstructed images indicate that the P-SPIR method can effectively mitigate the depth-of-interaction (DOI) effect, especially at the peripheral area of field-of-view (FOV). Furthermore, the method can be applied to PET scanners with any other structures and list-mode data format with high flexibility and efficiency.
- PSF

References

[1]	B. Karuta and R. Lecomte, IEEE Trans. Med. Imaging, 11(3):379-385 (1992)
[2]	V. Andrea, S. Nils, E. Lars et al, Eur. J. Nucl. Med. Mol. Imaging, 36(10):1639-1650 (2009)
[3]	J. Thies, Z. Vilia, S. Jessica et al, Eur. J. Nucl. Med. Mol. Imaging, 3(1):1-17 (2016)
[4]	T. Thonnapong, I. Yoko, S. Takahiro et al, Radiological Physics and Technology, 9(1):127-137 (2016)
[5]	K. Kazuya, K. Kenichi, T. Makiko et al, British journal of radiology, 89(1063):20150938 (2016)
[6]	V. Astakhov, P. Gumplinger, C. Moisan et al, IEEE Transactions on Nuclear Science, 50(5):1373-1378 (2003)
[7]	S. Salvador, D. Huss, D. Brasse et al, IEEE Transactions on Nuclear Science, 56(1):17-23 (2009)
[8]	M. Ito, J. S. Lee, S. I. Kwon et al, IEEE Transactions on Nuclear Science, 57(3):976-981 (2010)
[9]	V. Y. Panin, F. Kehren, H. Rothfuss et al, IEEE Transactions on Nuclear Science, 53(1):152-159 (2006)
[10]	S. Tong, A. M. Alessio and P. E. Kinahan. Phys. Med. Biol, 55(5):1453-1473 (2010)
[11]	K. Lee, P. E. Kinahan, J. A. Fessler et al, Phys. Med. Biol, 49(19):4563-4578 (2004)
[12]	K. Saha, K. J. Straus, Y. Chen et al, J. Appl. Phys, 116(8) (2014)
[13]	J. Qi, R. M. Leahy, S. R. Cherry et al, Phys. Med. Biol, 43(4):1001-1013 (1998)
[14]	R. T. Yao, R. M. Ramachandra, N. Mahajan et al, Phys. Med. Biol, 57(21):6827-6848 (2012)
[15]	A. Lougovski, F. Hofheinz, J. Maus et al, Phys. Med. Biol, 59(3):561-577 (2014)
[16]	X. Fan, H. P. Wang, M. K. Yun et al, Chin. Phys. B, 24(1):500-542 (2015)
[17]	K. Assi, V. Breton, I. Buvat et al, Nucl. Instrum. Methods Phys. Res., Sect. A, 527(1):180-189 (2004)
[18]	M. Caadas, P. Arce, M. P. Rato, Phys. Med. Biol, 56(1):273-288 (2011)
[19]	National Electrical Manufacturers Association (NEMA), NEMA Standards Publication NU 4-2008:Performance Measurement for Small Animal Positron Emission Tomographs (Washington, DC:NEMA, 2008)
[20]	I. J. Ahn, J. H. Kim, Y. J. Chang et al, IEEE Transactions on Nuclear Science, 62(3):859-868 (2015)
[21]	M. Rafecas, B. Mosler, M. Dietz et al, IEEE Transactions on Nuclear Science, 51(5):2597-2605 (2004)
[22]	F. R. Rannou, A. F. Chatziioannou, IEEE Symposium Conference Record Nuclear Science 2004, 6:3433-3436 (2004)
[23]	J. D. Leroux, C. Thibaudeau, R. Lecomte and R. Fontaine, 2007 IEEE Nuclear Science Symposium Conference Record, 5:3644-3648 (2007)
[24]	F. Boisson, C. J. Wimberley, W. Lehnert et al, Phys. Med. Biol, 58(19):6749-6763 (2013)
[25]	L. Y. Wang, J. Zhu, X. Liang et al, Phys. Med. Biol, 60(1):137-150 (2015)
[26]	J. Zhou and J. Y. Qi, Phys. Med. Biol, 56(20):6739-6757 (2011)
[27]	M. Aykac, V. Y. Panin, I. Hong and M. E. Casey. 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference, 1-5 (2014)

Access

Get Citation

null. Fast and accurate generation method of PSF-based system matrix for PET reconstruction[J]. Chinese Physics C, 2017, 41(4): 048201. doi: 10.1088/1674-1137/41/4/048201

null. Fast and accurate generation method of PSF-based system matrix for PET reconstruction[J]. Chinese Physics C, 2017, 41(4): 048201. doi: 10.1088/1674-1137/41/4/048201 shu

RIS(for EndNote,Reference Manager,ProCite)

BibTex

Txt

Milestone

Received: 2016-08-20

Fund

null

Article Metric

Article Views(1529)
PDF Downloads(74)
Cited by(0)

Policy on re-use

To reuse of subscription content published by CPC, the users need to request permission from CPC, unless the content was published under an Open Access license which automatically permits that type of reuse.

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Fast and accurate generation method of PSF-based system matrix for PET reconstruction

null

Received Date: 2016-08-20
Available Online: 2017-04-05

Fund Project: null

Abstract: This work investigates the positional single photon incidence response (P-SPIR) to provide an accurate point spread function (PSF)-contained system matrix and its incorporation within the image reconstruction framework. Based on the Geant4 Application for Emission Tomography (GATE) simulation, P-SPIR theory takes both incidence angle and incidence position of the gamma photon into account during crystal subdivision, instead of only taking the former into account, as in single photon incidence response (SPIR). The response distribution obtained in this fashion was validated using Monte Carlo simulations. In addition, two-block penetration and normalization of the response probability are introduced to improve the accuracy of the PSF. With the incorporation of the PSF, the homogenization model is then analyzed to calculate the spread distribution of each line-of-response (LOR). A primate PET scanner, Eplus-260, developed by the Institute of High Energy Physics, Chinese Academy of Sciences (IHEP), was employed to evaluate the proposed method. The reconstructed images indicate that the P-SPIR method can effectively mitigate the depth-of-interaction (DOI) effect, especially at the peripheral area of field-of-view (FOV). Furthermore, the method can be applied to PET scanners with any other structures and list-mode data format with high flexibility and efficiency.