Performance analysis of quantitative phase retrieval method in Zernike phase contrast X-ray microscopy

Heng Chen; Kun Gao; Da-Jiang Wang; Li Song; Zhi-Li Wang

doi:10.1088/1674-1137/40/2/029001

Chinese Physics C> 2016, Vol. 40> Issue(2) : 029001 DOI: 10.1088/1674-1137/40/2/029001

Performance analysis of quantitative phase retrieval method in Zernike phase contrast X-ray microscopy

Heng Chen ^1,2 ,
Kun Gao ² ,
Da-Jiang Wang ² ,
Li Song ² ,
Zhi-Li Wang ^2,,

1.
Department of Physics, University of Science and Technology of China, Hefei 230026, China
2.
National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei 230029, China
3.
National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei 230029, China

Abstract
HTML
Reference
Related

PDF

Abstract：
Since the invention of Zernike phase contrast method in 1930, it has been widely used in optical microscopy and more recently in X-ray microscopy. Considering the image contrast is a mixture of absorption and phase information, we recently have proposed and demonstrated a method for quantitative phase retrieval in Zernike phase contrast X-ray microscopy. In this contribution, we analyze the performance of this method at different photon energies. Intensity images of PMMA samples are simulated at 2.5 keV and 6.2 keV, respectively, and phase retrieval is performed using the proposed method. The results demonstrate that the proposed phase retrieval method is applicable over a wide energy range. For weakly absorbing features, the optimal photon energy is 2.5 keV, from the point of view of image contrast and accuracy of phase retrieval. On the other hand, in the case of strong absorption objects, a higher photon energy is preferred to reduce the error of phase retrieval. These results can be used as guidelines to perform quantitative phase retrieval in Zernike phase contrast X-ray microscopy with the proposed method.
- X-ray microscopy ,
- Zernike phase contrast ,
- quantitative phase retrieval

References

[1]	F. Zernike, Physica, 9 (10): 974-986 (1942)
[2]	G. Schmahl, D. Rudolph, P. Guttmann et al, Rev. Sci. Instrum., 66 (2): 1282-1286 (1995)
[3]	C. Holzner, M. Feser, S. Vogt et al, Nat. Phys., 6 (11): 883-887 (2010)
[4]	M. Stampanoni, R. Mokso, F. Marone et al, Phys. Rev. B, 81 (14): 140105 (2010)
[5]	D. Wang, N. Li, Z. Wang et al, J. Synchrotron Rad., 21 (5): 1175-1179 (2014)
[6]	M. Awaji, Y. Suzuki, A. Takeuchi et al, J. Synchrotron Rad., 9 (3): 125-127 (2002)
[7]	H. S. Youn and S. W. Jung, J. Microsc., 223 (1): 53-56 (2006)
[8]	A. Tkachuk, F. Duewer, H. Cui et al, Z. Kristallogr., 222 (11): 650-655 (2007)
[9]	Y. Liu, J. C. Andrews, J. Wang et al, Opt. Express, 19(2): 540-545 (2011)
[10]	Q. Yuan, K. Zhang, Y. Hong et al, J. Synchrotron Rad., 19 (6): 1021-1028 (2012)
[11]	Z. Wang, K. Gao, J. Chen et al, Biotechnol. Adv., 31 (3): 387-392 (2013)
[12]	I. Vartiainen, M. Warmer, D. Goeries et al, J. Synchrotron Rad., 21 (4): 790-794 (2014)
[13]	Y. Yang, R. Heine, Y. Cheng et al, Appl. Phys. Lett., 105 (9): 094101 (2014)
[14]	Y. T. Chen, T. Y. Chen, J. Yi et al, Opt. Lett., 36 (7): 1269-1271 (2011)
[15]	I. Vartiainen, R. Mokso, M. Stampanoni et al, Opt. Lett., 39 (6): 1601-1604 (2014)
[16]	T. Y. Chen, Y. T. Chen, C. L. Wang et al, Opt. Express, 19 (21): 19919-19924 (2011)
[17]	G. C. Yin, F. R. Chen, Y. Hwu et al, Appl. Phys. Lett., 90 (18): 181118 (2007)
[18]	H. Chen, Z. Wang, K. Gao et al, J. Synchrotron Rad., 22 (4): 1056-1061 (2015)

[1]	Guang-Lei Wang , Wei-Qing Zhang , Xue-Ming Yang , Chao Feng , Hai-Xiao Deng . Fully coherent hard X-ray generation by two-stage phase-merging enhanced harmonic generation. Chinese Physics C, 2016, 40(9): 098101. doi: 10.1088/1674-1137/40/9/098101
[2]	Hua-Jie Han , Sheng-Hao Wang , Kun Gao , Zhi-Li Wang , Can Zhang , Meng Yang , Kai Zhang , Pei-Ping Zhu . Preliminary research on dual-energy X-ray phase-contrast imaging. Chinese Physics C, 2016, 40(4): 048201. doi: 10.1088/1674-1137/40/4/048201
[3]	ZHOU Hou-Bing , DONG Guo-Xiang , SUN Xiao-Jun , XU Fu-Rong . Phase transition in odd-N Pd-isotopes. Chinese Physics C, 2015, 39(11): 114103. doi: 10.1088/1674-1137/39/11/114103
[4]	WANG Rui , CHEN Ying , GONG Ming , LIU Chuan , LIU Yu-Bin , LIU Zhao-Feng , MA Jian-Ping , MENG Xiang-Fei , ZHANG Jian-Bo . Phase transition in finite density and temperature lattice QCD. Chinese Physics C, 2015, 39(6): 063103. doi: 10.1088/1674-1137/39/6/063103
[5]	JIA Quan-Jie , CHEN Yu , LI Gang , JIANG Xiao-Ming . Optimization of the in-line X-ray phase-contrast imaging setup considering edge-contrast enhancement and spatial resolution. Chinese Physics C, 2012, 36(3): 267-274. doi: 10.1088/1674-1137/36/3/014
[6]	WANG Fang , LIN Lin , ZHANG He , HAO Jian-Kui , ZHANG Bao-Cheng , LIU Ke-Xin . Amplitude and phase stability studies in a DC superconducting injector. Chinese Physics C, 2011, 35(9): 855-858. doi: 10.1088/1674-1137/35/9/013
[7]	ZHANG Feng , GAO Yuan-Ning , HUO Lei . Comment on phase conventions in helicity formalism. Chinese Physics C, 2011, 35(5): 426-428. doi: 10.1088/1674-1137/35/5/003
[8]	LI Zheng-Hong , XIE Hong-Quan . RF phase jitter in a klystron amplifier. Chinese Physics C, 2011, 35(9): 851-854. doi: 10.1088/1674-1137/35/9/012
[9]	XU Xiao-Mei , FU Yong-Ping , LI Yun-De . η string formation in QCD chiral phase transition. Chinese Physics C, 2010, 34(4): 444-447. doi: 10.1088/1674-1137/34/4/004
[10]	MAO Shi-Jun , HUANG Xu-Guang , ZHUANG Peng-Fei . Viscosities in chiral symmetry breaking phase. Chinese Physics C, 2010, 34(9): 1440-1442. doi: 10.1088/1674-1137/34/9/065
[11]	LI Ang , PENG Guang-Xiong , Lombardo U . Deconfinement phase transition in neutron star matter. Chinese Physics C, 2009, 33(S1): 61-63. doi: 10.1088/1674-1137/33/S1/020
[12]	LIU Rong , WANG Zheng , PAN Wei-Min , WANG Guang-Wei , LIN Hai-Ying , SHA Peng , ZENG Ri-Hua . FPGA-based amplitude and phase detection in DLLRF. Chinese Physics C, 2009, 33(7): 594-598. doi: 10.1088/1674-1137/33/7/017
[13]	LIU Ying-Xin , QIN Shan , WU Jing , LI Xiao-Dong , LI Yan-Chun , LIU Jing . Pressure-induced phase transition of wulfenite. Chinese Physics C, 2009, 33(11): 1023-1027. doi: 10.1088/1674-1137/33/11/019
[14]	WEI Gao-Feng , LONG Chao-Yun , LONG Zheng-Wen , QIN Shui-Jie , FU Qiang . Classical mechanics in non-commutative phase space. Chinese Physics C, 2008, 32(5): 338-341. doi: 10.1088/1674-1137/32/5/002
[15]	WANG Jian-Hua , LI Kang , Dulat Sayipjamal , . Klein-Gordon oscillators in noncommutative phase space. Chinese Physics C, 2008, 32(10): 803-806. doi: 10.1088/1674-1137/32/10/007
[16]	YANG Fang , SHEN Hong . Hadron-quark phase transition in neutron stars. Chinese Physics C, 2008, 32(S2): 77-80.
[17]	YU Ai-Min , LI Zheng , ZHANG Di , HUANG Zhi-Feng . In-Line Phase Contrast Imaging Using a Micro-focus X-Ray Source. Chinese Physics C, 2006, 30(11): 1119-1122.
[18]	CHEN Zhi-Hua , PAN Lin , LI Gang , XU Mei , XU Bo , ZHAO Tian-De , CHEN Wei-Chang , TANG Jin-Tian . Phase-Contrast Imaging with Synchrotron X-ray for Mouse Lung. Chinese Physics C, 2003, 27(S1): 83-85.
[19]	Liu Baohua , Li Jiarong . The Mean-Field Analysis for Chiral Symmetry Phase Transition. Chinese Physics C, 1988, 12(S4): 373-378.
[20]	Wu Chongshi , Zeng Jinyan . Nuclear Pairing Phase Transition. Chinese Physics C, 1988, 12(S1): 81-90.

Access

Get Citation

Heng Chen, Kun Gao, Da-Jiang Wang, Li Song and Zhi-Li Wang. Performance analysis of quantitative phase retrieval method in Zernike phase contrast X-ray microscopy[J]. Chinese Physics C, 2016, 40(2): 029001. doi: 10.1088/1674-1137/40/2/029001

RIS(for EndNote,Reference Manager,ProCite)

BibTex

Txt

Milestone

Received: 2015-04-29
Revised: 2015-08-26

Fund

Supported by the State Key Project for Fundamental Research (2012CB825801), National Natural Science Foundation of China (11475170, 11205157 and 11179004) and Anhui Provincial Natural Science Foundation (1508085MA20)

Article Metric

Article Views(3090)
PDF Downloads(344)
Cited by(0)

Policy on re-use

To reuse of subscription content published by CPC, the users need to request permission from CPC, unless the content was published under an Open Access license which automatically permits that type of reuse.

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Performance analysis of quantitative phase retrieval method in Zernike phase contrast X-ray microscopy

Corresponding author: Zhi-Li Wang,

1. Department of Physics, University of Science and Technology of China, Hefei 230026, China

2. National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei 230029, China

3. National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei 230029, China

Received Date: 2015-04-29

Accepted Date: 2015-08-26

Available Online: 2016-02-20

Fund Project: Supported by the State Key Project for Fundamental Research (2012CB825801), National Natural Science Foundation of China (11475170, 11205157 and 11179004) and Anhui Provincial Natural Science Foundation (1508085MA20)

Abstract: Since the invention of Zernike phase contrast method in 1930, it has been widely used in optical microscopy and more recently in X-ray microscopy. Considering the image contrast is a mixture of absorption and phase information, we recently have proposed and demonstrated a method for quantitative phase retrieval in Zernike phase contrast X-ray microscopy. In this contribution, we analyze the performance of this method at different photon energies. Intensity images of PMMA samples are simulated at 2.5 keV and 6.2 keV, respectively, and phase retrieval is performed using the proposed method. The results demonstrate that the proposed phase retrieval method is applicable over a wide energy range. For weakly absorbing features, the optimal photon energy is 2.5 keV, from the point of view of image contrast and accuracy of phase retrieval. On the other hand, in the case of strong absorption objects, a higher photon energy is preferred to reduce the error of phase retrieval. These results can be used as guidelines to perform quantitative phase retrieval in Zernike phase contrast X-ray microscopy with the proposed method.

HTML

Reference (18)

Performance analysis of quantitative phase retrieval method in Zernike phase contrast X-ray microscopy

Abstract：

References

Access

Article Metrics

Metrics

通讯作者: 陈斌, bchen63@163.com

Email This Article