Attenuation correction with region growing method used in the positron emission mammography imaging system

GU Xiao-Yue; LI Lin; YIN Peng-Fei; YUN Ming-Kai; CHAI Pei; HUANG Xian-Chao; SUN Xiao-Li; WEI Long

doi:10.1088/1674-1137/39/10/108202

Chinese Physics C> 2015, Vol. 39> Issue(10) : 108202 DOI: 10.1088/1674-1137/39/10/108202

Attenuation correction with region growing method used in the positron emission mammography imaging system

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Abstract：
The Positron Emission Mammography imaging system (PEMi) provides a novel nuclear diagnosis method dedicated for breast imaging. With a better resolution than whole body PET, PEMi can detect millimeter-sized breast tumors. To address the requirement of semi-quantitative analysis with a radiotracer concentration map of the breast, a new attenuation correction method based on a three-dimensional seeded region growing image segmentation (3DSRG-AC) method has been developed. The method gives a 3D connected region as the segmentation result instead of image slices. The continuity property of the segmentation result makes this new method free of activity variation of breast tissues. The threshold value chosen is the key process for the segmentation method. The first valley in the grey level histogram of the reconstruction image is set as the lower threshold, which works well in clinical application. Results show that attenuation correction for PEMi improves the image quality and the quantitative accuracy of radioactivity distribution determination. Attenuation correction also improves the probability of detecting small and early breast tumors.

References

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GU Xiao-Yue, LI Lin, YIN Peng-Fei, YUN Ming-Kai, CHAI Pei, HUANG Xian-Chao, SUN Xiao-Li and WEI Long. Attenuation correction with region growing method used in the positron emission mammography imaging system[J]. Chinese Physics C, 2015, 39(10): 108202. doi: 10.1088/1674-1137/39/10/108202

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Received: 2014-12-18
Revised: 2015-06-15

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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

Attenuation correction with region growing method used in the positron emission mammography imaging system

Corresponding author: GU Xiao-Yue,

Received Date: 2014-12-18

Accepted Date: 2015-06-15

Available Online: 2015-10-10

Abstract: The Positron Emission Mammography imaging system (PEMi) provides a novel nuclear diagnosis method dedicated for breast imaging. With a better resolution than whole body PET, PEMi can detect millimeter-sized breast tumors. To address the requirement of semi-quantitative analysis with a radiotracer concentration map of the breast, a new attenuation correction method based on a three-dimensional seeded region growing image segmentation (3DSRG-AC) method has been developed. The method gives a 3D connected region as the segmentation result instead of image slices. The continuity property of the segmentation result makes this new method free of activity variation of breast tissues. The threshold value chosen is the key process for the segmentation method. The first valley in the grey level histogram of the reconstruction image is set as the lower threshold, which works well in clinical application. Results show that attenuation correction for PEMi improves the image quality and the quantitative accuracy of radioactivity distribution determination. Attenuation correction also improves the probability of detecting small and early breast tumors.

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Attenuation correction with region growing method used in the positron emission mammography imaging system

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