Calculating Dose-Depth Curve of Intermediate Energy Heavy lon

  • Tumor treatment with heavy ion is characterized by the depth-dose curve of heavy ions. So,it is a key to develop physics model for calculating dose. In this paper, the media for calculation have been selected from the chemical component of biological cells,characters of radiobiology and demand of physical dose calculation. A method to calculate does-depth distribution has been developed by using the semi-empirical functions of nuclear fragmentation reaction cross section and total nuclear reaction cross section,and also considering other factors which affect the results of calculation. The results of calculation tally with experimental data and show that the theoretic calculation can be used in the tumor treatment and radiobiology effect research.
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  • [1] Birge A C et al. Heavy Charged-particle Beams, In: Radiation Dosimetry. New York: Academic Press Inc., 1956, 6232 WEI Zeng-Quan. Trends in Nuclear Physics, 1994, 11(3): 44(in Chinese)(卫增泉. 核物理动态, 1994, 11(3): 44)3 Tsujii H et al. Book of Abstracts, 5th Workshop on Heavy Charged Particles in Biology and Medicine. Darmstadt, Germany: GSI, 1995, 1674 Kraft G. Radiobiology of Heavy Charged Particles, GS1-Preprint-96-60, Nov. 19965 Hirao Y et a]. HIMAC-001, Dec. 1992, 1-386 Kraft G. What Kind of Radiobiology Should Be Done at A Hadmn Therapy Center, GSI-Preprint-97-05, Jan. 19977 LI Qiang et al. Nuclear Physics Review, l997, 14(4): 243(in Chinese)(李强等. 原子核物理评论. 1997, 14(4): 243)8 ZHAO Dong-Hui et al. Medical Treatment Instrument of World, 1996, 2(11): 48(in Chinese)(赵东辉等. 世界医疗器械, 1996, 200: 48)9 Sihver L et al. LAIRS-M-103, HIMAC-008, Nov.14-16, 1994, 24110 Evans R D. The Atomic Nucleus. New York: McGraw-Hill Inc., 195511 DANG Bing-Rong. Nuclear Fragment Produced in Biological Tissue by Intermediate Energy Heavy Ion. Ph. D. Thesis, Institute of Modem Physics, The Chinese Academy of Sciences, 2001 (in Chinese)(党秉荣, 中能重离子在生物组织中产生的核碎. 中国科学院近代物理研究所博士论文, 2001年)12 Summerer K et al. Phys. Rev., 1990. C42: 254613 Kraft G et al. Adv. Radiat. Biol., 1993, 17: 114 Kanai T et al. Irradiation of 135MeV/u Carbon and Neon Beams for Studies of Radiation Biology, HIMAC-004, 1993
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DANG Bing-Rong, WEI Zeng-Quan and LI Wen-Jian. Calculating Dose-Depth Curve of Intermediate Energy Heavy lon[J]. Chinese Physics C, 2002, 26(4): 430-434.
DANG Bing-Rong, WEI Zeng-Quan and LI Wen-Jian. Calculating Dose-Depth Curve of Intermediate Energy Heavy lon[J]. Chinese Physics C, 2002, 26(4): 430-434. shu
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Received: 2001-04-09
Revised: 1900-01-01
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Calculating Dose-Depth Curve of Intermediate Energy Heavy lon

    Corresponding author: DANG Bing-Rong,
  • Institute of Modern Physics,The Chinese Academy of Sciences,Lanzhou 730000,China

Abstract: Tumor treatment with heavy ion is characterized by the depth-dose curve of heavy ions. So,it is a key to develop physics model for calculating dose. In this paper, the media for calculation have been selected from the chemical component of biological cells,characters of radiobiology and demand of physical dose calculation. A method to calculate does-depth distribution has been developed by using the semi-empirical functions of nuclear fragmentation reaction cross section and total nuclear reaction cross section,and also considering other factors which affect the results of calculation. The results of calculation tally with experimental data and show that the theoretic calculation can be used in the tumor treatment and radiobiology effect research.

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